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Chemotaxis of large field of cells
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Aggregation of D. discoideum amoebae towards a point source of the chemoattractant cAMP. The numbers on the upper left corner are minutes and seconds. From G. Gerisch, Max-Planck-Institut fur Biochemie, Martinsried, Germany. |
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Aggregation of D. discoideum ameobae towards cAMP, lower magnification. From R. Firtel, University of California, San Diego |
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Chemotaxis of single cells towards a point source of the chemoattractant cAMP. The numbers on the upper left corner are minutes and seconds. From G. Gerisch, Max-Planck-Institut fur Biochemie, Martinsried, Germany. |
Dynamic Reorganization of Actin in chemotaxing cells.
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Actin shows dynamic reorganization in the leading edge of cells migrating under the influence of cAMP. Actin is visualized by and Actin binding domain GFP fusion made in David Knecht's laboratory (Univ. Conn.). From R. Firtel, UCSD. |
Steps cell movement in aggregation
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Time-lapse video of small group of aggregating cells. Interval between movement steps is 6 minute. From P. Devreotes, Johns Hopkins Medical Institutions.
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Dark- field Waves of cell shape change in aggregation
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Time-lapse video of monolayer of aggregating cells filmed through a dark-field macroscope. White bands represent chemotactically oriented cells. Period of wave initiation is 6 minutes. From P. Devreotes, Johns Hopkins Medical Institutions. |
Movement of Cells Into an Aggregate
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Under the influence of cAMP, cells form streams which participate in the formation of a multicellular tissue by chemotaxis. From R. Firtel, UCSD. |
Movement of Cells During Morphogenesis
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Time-lapse video showing slug formation, migration and culmination. From R. Chisholm, Northwestern University. |