Welcome to the GenomeWeb
Materials & Culture Collections

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Many organisations make collections of biological material available. These are pages that provide online databases of their collections.


[info] ATCC American Type Culture Collection
[info] Anderson's Timesaving Comparative Guides
[info] Research Genetics
[info] Genome Systems
[info] Developmental Studies Hybridoma Bank
[info] WDCM Strains and Culture Collections (Japan)
[info] Invitrogen
[info] HyperCLDB
[info] MSDN - Microbial Strain Data Network
[info] Centraalbureau voor Schimmelcultures (CBS)
[info] IGeR - YAC Screening Centre and TIGEM
[info] Resource Centre of the German Human Genome Project (RZPD)
[info] Coriell Institute for Medical Research
[info] CABRI (Common Access to Biotechnological Resources and Information)

Specific Resources

[info] Molecular Probe Data Base (MPDB)
[info] UK HGMP Primers Database
[info] HGMP-RC UK DNA Probe Bank
[info] NIGMS Human Genetic Mutant Cell Repository
[info] The Autism Research Resource
[info] NIA Aging Cell Repository
[info] ECACC European Collection of Animal Cell Cultures
[info] Oligonucleotide Probe Database: OPD
[info] The Antibody Resource Page
[info] BacPac Resource Center
[info] Human Biological Data Interchange (HBDI)
[info] National Disease Research Interchange (NDRI)
[info] List of Bacterial Names with Standing in Nomenclature
[info] The National Laboratory for the Genetics of Isreali Populations

Species-Specific Stock Centres

[info] E.coli Stock Genetic Centre
[info] Nottingham Arabidopsis Stock Centre
[info] Salmonella Genetic Stock Centre (SGSC)
[info] National Collection of Yeast Cultures

Detailed information on the above options

ATCC American Type Culture Collection
ATCC is a global bioscience organization that provides biological products, technical services, and educational programs to private industry, government, and academic organizations around the world. The mission of the ATCC is to acquire, authenticate, and maintain reference cultures, related biological materials, and associated data, and to distribute these to qualified scientists in government, industry, and education.

Anderson's Timesaving Comparative Guides
Lists of Reagents and Suppliers are maintained here to facilitate tracking down:

Information in most areas contains sizes, concentrations, porosity and a catalog number. There are links to contact information pages and company home pages if they have a web site.

Research Genetics

Genome Systems
Commercial company supplying

Developmental Studies Hybridoma Bank
The Developmental Studies Hybridoma Bank supplies investigators with monoclonal antibodies useful for studies in developmental and cell biology. They may be ordered as tissue culture supernatants, ascites, or partially purified immunoglobulin; selected hybridomas are also available.

WDCM Strains and Culture Collections (Japan)
WFCC World Data Centre for Microorganisms (WDCM) provides a comprehensive directory of culture collecions, databases on microbes and cell lines, and the gateway to biodiversity, molecular biology and genome projects.

WDCM is maintained by the Japan Federation for Culture Collections (JFCC).

Invitrogen is a commercial service. This link provides:

HyperCLDB is the hypertext version of the Cell Line Data Base, devoted to information on availability of human and animal cell lines within European collections and laboratories.

MSDN - Microbial Strain Data Network
The Microbial Strain Data Network, MSDN provides communication and information services to scientists worldwide, principally within the microbiology and biotechnology communities. It is a non-profit making organisation as any income received from networking activities are used to further develop the network.

It has a large collection of catalogues and strain data.

Centraalbureau voor Schimmelcultures (CBS)
The Centraalbureau voor Schimmelcultures is one of the world's largest service and research collections of filamentous fungi and yeasts. The collection comprises about 35,000 strains. Research of the CBS concentrates on taxonomy and phylogeny of selected groups throughout the Kingdom of Fungi. CBS also offers services like identification, contract research, supply of cultures.

IGeR - YAC Screening Centre and TIGEM
The YAC Screening Centre and TIGEM at San Raffaele Biomedical Science Park (Milan, Italy) have coordinated their efforts in order to provide a wide range of resources and services for scientists engaged in genome mapping and gene isolation studies.

The services provided by YSC are free of charge for Italian academic users. The services provided by the YAC Screening Centre will be charged to Italian commercial users and to all non-Italian users.

Resource Centre of the German Human Genome Project (RZPD)
This provides many biological services, including:

Coriell Institute for Medical Research
The mission of the Coriell Institute for Medical Research is to conduct and support scientific research and educational programs on the causes, prevention, and cure of disease through the study of cells and their molecular components, and through propagation, storage and distribution of human cell cultures and their molecular components.

CABRI (Common Access to Biotechnological Resources and Information)
The CABRI (Common Access to Biotechnological Resources and Information) Project aims to meet the need of European biotechnology research and development for high quality biological resources by providing common access for the user via the Internet to the resources and information of the providers within the project.

It is further intended that a user, having located an item of interest, should be able to obtain it from the Resource Centre concerned using an Internet based ordering system.

CABRI will refine tools and test the formation of an integrated resource centre service linking catalogue databases of different organism types, genetic materials and other "biologicals" in Europe so that the user world-wide can access these relevant catalogues during one searching session through a common entry point and request/order products to be delivered to their place of work.

Molecular Probe Data Base (MPDB)
The Molecular Probe Data Base (MPDB) contains information on ca. 4300 synthetic oligonucleotides with a sequence of up to 100 nucleotides. Data are mainly taken from the literature and are encoded on the basis of controlled vocabularies.



UK HGMP Primers Database
The UK HGMP Resource Centre supplies human and mouse DNA primers to its users. This is a database of primers that have already been constructed.

The HGMP-RC supplies DNA probes for human, mouse and other species.

NIGMS Human Genetic Mutant Cell Repository
Cell Types

Cell Culture Collections DNA Collections

The Autism Research Resource
A genetic resource of DNA samples to support the study of autism in families where more than one child is affected or where one child is affected and one demonstrates another significant and related developmental disorder has been built at the Coriell Institute for Medical Research in collaboration with the clinical services at the University of Medicine and Dentistry Robert Wood Johnson Medical School. An open bank of anonymously collected materials documented by a detailed clinical diagnosis forms the basis of this growing database of information about the disease. Three criteria were used to assess the autistic phenotype. These include the ADI (Autism Diagnostic Interview), the ADOS (Autism Diagnostic Observational Schedule-Generic), and the DSM IV Diagnostic Criteria for 299.00 Autistic Disorder. All clinical interviews were conducted face-to-face. For each donor subject tested, a representative Autistic Diagnostic Criteria Score Sheet used to collect data is provided. Currently, the resource contains 20 families in which 41 individuals have been examined. Thirty-three of these individuals have a diagnosis of autistic disorder by two or more criteria; 28 of these satisfy all three criteria. There are 20 affected sib pairs with a diagnosis of autistic disorder by two or more criteria; 9 of these pairs meet the criteria for autistic disorder by all three criteria.

NIA Aging Cell Repository
The Repository has human cell cultures from individuals with aging-related conditions. These include disorders of accelerated aging (e.g., progeria, Werner syndrome, Cockayne syndrome, Rothmund-Thomson syndrome, and Down syndrome) and cell cultures from familial Alzheimer disease extended pedigrees. The collection also includes specially characterized normal human diploid fibroblast cultures (IMR90 and IMR91) and over 500 skin fibroblast cultures from subjects participating in the NIA-sponsored Gerontology Research Center Baltimore Longitudinal Study of Aging. In addition, the Aging Cell Repository has human and animal differentiated cell cultures (epithelial, endothelial, and smooth muscle), human mammary epithelial and keratinocyte cell cultures, and fibroblast cultures from animals with different life spans. Menus are provided to allow users to search for cell cultures in a variety of ways including Repository number, MIM number, disease description, as well as sample type and animal species.

ECACC European Collection of Animal Cell Cultures
The European Collection of Cell Cultures (ECACC) was established in 1984 and accepts cell lines of diverse origins either for addition to its collections, or as a patent or safe deposit.

Collection deposits are made available worldwide for use by research and industry. Through its expertise in handling cell lines, ECACC is in a unique position to offer services to clients in many areas of cell technology, characterisation and standardisation.

Oligonucleotide Probe Database: OPD
OPD is a hyperlinked database of oligonucleotide sequences and associated experimental information which may be useful to scientists interested in using oligonucleotide probes in their research.

OPD contains data for: (1) probe design, (2) probe characterization studies (temperature of dissociation studies using membrane hybridizations), (3) probe specificity studies, (4) use of probes for in situ hybridizations, (5) use of primers for PCR, and (6) specificity of PCR primers.

The Antibody Resource Page
This is devoted to bringing together the vast number of resources about antibodies on the net. It includes links to educational websites, links to on-line companies (more than 30) that sell antibodies and antibody-related products, links to antibody-related databases, essays on antibody-related topics, and more.

BacPac Resource Center
This is a World Wide Web site run by the BacPac Resource Center in the Department of Human Genetics at Roswell Park Cancer Institute in Buffalo, New York, USA. It contains information on currently available BAC and PAC genomic DNA libraries; high density colony hybridization filters, BAC/PAC cloning vectors, laboratory staff info, and pertinent recent publications.

Human Biological Data Interchange (HBDI)
The Human Biological Data Interchange (HBDI), is program of the non-profit National Disease Research Interchange.

National Disease Research Interchange (NDRI)
The National Disease Research Interchange (NDRI) is a unique nonprofit organization engaged in the procurement and distribution of human tissues and organs for biomedical researchers primarily in the USA.

Three programs comprise NDRI, each with objectives relevant to different aspects of scientific research. They are, as follows:

The Human Tissues and Organs for Research (HTOR) program focuses on the retrieval and distribution of tissues and organs from autopsy and surgical procedures, as well as specimens obtained from eye and tissue banks. Examples include whole and partial organs, such as, heart, kidney, lung, brain, liver, eyes, and bones and joints for biomechanical and orthopedic studies.

The Human Biological Data Interchange (HBDI) is NDRI's model for the development of genetically valuable family collections for use in the advancement and study of the genetic basis for disease. It was developed as a resource to provide to diabetes researchers, family and medical history information, immortalized cell lines and DNA from families with Type I diabetes. The HBDI repository currently holds biomaterials from over 500 families; the HBDI database contains family and medical history data on over 6,500 families with diabetes. Researchers may request a catalog of these families in the repository and access confidentiality coded information from these family and medical histories.

Odyssey One was established to respond to the new and emerging needs of researchers in innovative areas related to the use of human materials in research. Among these areas are the use of islet cells for pancreatic transplant research, malignant tumors and normal adjacent tissue for cancer research, and bone marrow stem cells for a wide variety of research applications.

List of Bacterial Names with Standing in Nomenclature
The List of Bacterial Names with Standing in Nomenclature includes, alphabetically and chronologically, the official nomenclature of bacteria and the nomenclatural changes as cited in the Approved Lists of Bacterial Names, or published, or validated in the International Journal of Systematic Bacteriology. It is extensively annotated to clarify the Rules which govern the scientific nomenclature.

For more information, see International Journal of Systematic Bacteriology, 1997, 47, 590-592.

The National Laboratory for the Genetics of Isreali Populations
The National Laboratory for the Genetics of Israeli Populations was initiated in 1994 by the Israel Academy of Sciences and Humanities. It is located at the Sackler Faculty of Medicine, on the Tel-Aviv University campus. The laboratory is a national repository for human cell lines, representing the unique and large ethnic variation of the Israeli populations. We concentrate on collecting and establishing human cell lines representing the various ethnic groups in Israel. We also collect cell lines from individuals and families affected by genetic disorders unique to Israeli populations.

The human cell lines and DNA samples in our collection may be used for research purposes only.

E.coli Stock Genetic Centre
The E.coli Stock Genetic Centre provides genetic information, including genotypes and reference information for the several thousand strains in the CGSC collection, a gene list with map and gene product information, and information on specific mutations

Nottingham Arabidopsis Stock Centre
NASC now maintains several thousand unique lines of Arabidopsis thaliana. These include several hundred well characterised hormone, flowering, biochemical, form mutants and multiple marker lines. NASC distributes seed free of charge to Europe, Australia, Asia and Africa.

Salmonella Genetic Stock Centre (SGSC)
The SGSC maintains stocks of Salmonella. The largest numbers of strains (several thousand) are mutants of S.typhimurium LT2. The SGSC is supported by the Natural Sciences and Engineering Research Council of Canada. Strains are provided without charge to researchers at non-profit research establishments and universities; there is a charge for workers at commercial laboratories.

National Collection of Yeast Cultures
The National Collection of Yeast Cultures (NCYC) maintains over 2,700 non-pathogenic yeasts, including type strains, strains of general interest for education and research, strains of industrial importance and genetically marked strains.

There are extensive collections of brewing yeasts and genetically defined strains of Schizosaccharomyces pombe and Saccharomyces cerevisiae. Research associated with the Collection aims to improve techniques to identify and classify yeasts, particularly those associated with brewing and food spoilage.

The NCYC is a member of the European Culture Collections9 Organization (ECCO) and the World Federation for Culture Collections (WFCC) and offers a range of additional services including species identification and confidential safe deposit.

Any Comments, Questions? Support@hgmp.mrc.ac.uk