ENTRY       EC 6.3.5.1
NAME        NAD+ synthase (glutamine-hydrolysing)
            NAD+ synthetase (glutamine-hydrolysing)
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Carbon--nitrogen ligases with glutamine as amido-N-donor
SYSNAME     Deamido-NAD+:L-glutamine amido-ligase (AMP-forming)
REACTION    ATP + Deamido-NAD+ + L-Glutamine + H2O = AMP + Pyrophosphate +
            NAD+ + L-Glutamate
SUBSTRATE   ATP
            Deamido-NAD+
            L-Glutamine
            H2O
            NH3
PRODUCT     AMP
            Pyrophosphate
            NAD+
            L-Glutamate
COMMENT     NH3 can act instead of glutamine. (cf. EC 6.3.1.5).
PATHWAY     PATH: MAP00251  Glutamate metabolism
            PATH: MAP00760  Nicotinate and nicotinamide metabolism
GENES       MJA: MJ1352
            ECO: b1740(nadE)
            HPY: HP0329(nadE)
            BSU: nadE(outB)
            MGE: MG383(nadE)
            MPN: H03_orf248(nadE)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.5.1
            WIT (What Is There) Metabolic Reconstruction: 6.3.5.1
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