ENTRY       EC 6.3.4.13
NAME        Phosphoribosylamine--glycine ligase
            Phosphoribosylglycinamide synthetase
            Glycinamide ribonucleotide synthetase
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Other carbon--nitrogen ligases
SYSNAME     5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)
REACTION    ATP + 5-Phospho-D-ribosylamine + Glycine = ADP + Orthophosphate +
            N1-(5-Phospho-D-ribosyl)glycinamide
SUBSTRATE   ATP
            5-Phospho-D-ribosylamine
            Glycine
PRODUCT     ADP
            Orthophosphate
            N1-(5-Phospho-D-ribosyl)glycinamide
COMMENT     Formerly EC 6.3.1.3.
PATHWAY     PATH: MAP00230  Purine metabolism
DISEASE     MIM: 138440  Phosphoribosylglycinamide formyltransferase,
                         phosphoribosylglycinamide
MOTIF       PS: PS00184  R-F-G-D-P-E-x-Q
            PS: PS00373  G-x-[STM]-[IVT]-x-[FYWVQ]-[VMAT]-x-[DEVM]-x-[LIVM]-D-x-
                         G-x(2)-[LIVT]-x(6)-[LIVM]
GENES       MJA: MJ0937
            MTH: MTH1445
            ECO: b4005(purD)
            HIN: HI0888(purD)
            HPY: HP1218(purD)
            BSU: purD
            SYN: slr1159(purD)
            SCE: YGL234W(ADE5)
            HSA: GARS(GlyRS)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.4.13
            WIT (What Is There) Metabolic Reconstruction: 6.3.4.13
///