ENTRY EC 6.3.3.3
NAME Dethiobiotin synthase
CLASS Ligases
Forming carbon-nitrogen bonds
Cyclo-ligases
SYSNAME 7,8-Diaminononanoate:carbon-dioxide cyclo-ligase
(ADP-forming)
REACTION ATP + 7,8-Diaminononanoate + CO2 = ADP + Orthophosphate +
Dethiobiotin
SUBSTRATE ATP
7,8-Diaminononanoate
CO2
CTP
PRODUCT ADP
Orthophosphate
Dethiobiotin
CDP
COMMENT CTP has half the activity of ATP.
PATHWAY PATH: MAP00780 Biotin metabolism
GENES MJA: MJ1299
ECO: b0778(bioD)
HIN: HI1445(bioD-A) HI1550(bioD-B)
HPY: HP0029(bioD)
BSU: bioD
SYN: bioD) slr0523(ECOLI_745
SCE: YNR057C(BIO4)
STRUCTURES PDB: 1DAD 1DAE 1DAF 1DAG 1DAH 1DAI 1DBS 1DTS
DBLINKS University of Geneva ENZYME DATA BANK: 6.3.3.3
WIT (What Is There) Metabolic Reconstruction: 6.3.3.3
SCOP (Structural Classificaion of Proteins): 6.3.3.3
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