ENTRY       EC 6.3.2.8
NAME        UDP-N-acetylmuramate--alanine ligase
            UDP-N-acetylmuramoyl-L-alanine synthetase
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Acid--amino-acid ligases (peptide synthases)
SYSNAME     UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)
REACTION    ATP + UDP-N-acetylmuramate + L-Alanine = ADP + Orthophosphate +
            UDP-N-acetylmuramoyl-L-alanine
SUBSTRATE   ATP
            UDP-N-acetylmuramate
            L-Alanine
PRODUCT     ADP
            Orthophosphate
            UDP-N-acetylmuramoyl-L-alanine
COMMENT     Involved with EC 6.3.2.4, 6.3.2.7 and 6.3.2.9-10 in the
            synthesis of a cell-wall peptide.
PATHWAY     PATH: MAP00471  D-Glutamine and D-glutamate metabolism
            PATH: MAP00550  Peptideglycan biosynthesis
GENES       ECO: b0091(murC)
            HIN: HI1139(murC)
            HPY: HP0623(murC)
            BSU: murC(ytxF)
            SYN: slr1423(murC)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.2.8
            WIT (What Is There) Metabolic Reconstruction: 6.3.2.8
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