ENTRY EC 6.3.2.13
NAME UDP-N-acetylmuramoylalnyl-D-glutamate--2,6-diaminopimelate ligase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diamino
$pimelate synthetase
CLASS Ligases
Forming carbon-nitrogen bonds
Acid--amino-acid ligases (peptide synthases)
SYSNAME UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino
$heptanedioate ligase (ADP-forming)
REACTION ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate +
meso-2,6-Diaminoheptanedioate =
ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-
$gamma-glutamyl-meso-2,6-diaminoheptanedioate
SUBSTRATE ATP
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
meso-2,6-Diaminoheptanedioate
PRODUCT ADP
Orthophosphate
UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-
$diaminoheptanedioate
PATHWAY PATH: MAP00300 Lysine biosynthesis
PATH: MAP00550 Peptideglycan biosynthesis
GENES MTH: MTH530 MTH531 MTH532 MTH734
ECO: b0085(murE)
HIN: HI1133(murE)
HPY: HP1494(murE)
BSU: murE
SYN: slr0528(murE)
DBLINKS University of Geneva ENZYME DATA BANK: 6.3.2.13
WIT (What Is There) Metabolic Reconstruction: 6.3.2.13
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