ENTRY       EC 6.3.2.13
NAME        UDP-N-acetylmuramoylalnyl-D-glutamate--2,6-diaminopimelate ligase
            UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diamino
            $pimelate synthetase
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Acid--amino-acid ligases (peptide synthases)
SYSNAME     UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino
            $heptanedioate ligase (ADP-forming)
REACTION    ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate +
            meso-2,6-Diaminoheptanedioate =
            ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-
            $gamma-glutamyl-meso-2,6-diaminoheptanedioate
SUBSTRATE   ATP
            UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
            meso-2,6-Diaminoheptanedioate
PRODUCT     ADP
            Orthophosphate
            UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-
            $diaminoheptanedioate
PATHWAY     PATH: MAP00300  Lysine biosynthesis
            PATH: MAP00550  Peptideglycan biosynthesis
GENES       MTH: MTH530 MTH531 MTH532 MTH734
            ECO: b0085(murE)
            HIN: HI1133(murE)
            HPY: HP1494(murE)
            BSU: murE
            SYN: slr0528(murE)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.2.13
            WIT (What Is There) Metabolic Reconstruction: 6.3.2.13
///

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