ENTRY EC 6.3.1.5
NAME NAD+ synthase
NAD+ synthetase
CLASS Ligases
Forming carbon-nitrogen bonds
Acid--ammonia (or amine) ligases (amide synthases)
SYSNAME Deamino-NAD+:ammonia ligase (AMP-forming)
REACTION ATP + Deamino-NAD+ + NH3 = AMP + Pyrophosphate + NAD+
SUBSTRATE ATP
Deamino-NAD+
NH3
PRODUCT AMP
Pyrophosphate
NAD+
COMMENT L-Glutamine also acts, more slowly, as amido-donor (cf.
EC 6.3.5.1).
PATHWAY PATH: MAP00760 Nicotinate and nicotinamide metabolism
PATH: MAP00910 Nitrogen metabolism
GENES MJA: MJ1352
MTH: MTH1510
DBLINKS University of Geneva ENZYME DATA BANK: 6.3.1.5
WIT (What Is There) Metabolic Reconstruction: 6.3.1.5
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