ENTRY       EC 6.2.1.25
NAME        Benzoate--CoA ligase
CLASS       Ligases
            Forming carbon-sulfur bonds
            Acid--thiol ligases
SYSNAME     Benzoate:CoA ligase (AMP-forming)
REACTION    ATP + Benzoate + CoA = AMP + Pyrophosphate + Benzoyl-CoA
SUBSTRATE   ATP
            Benzoate
            CoA
            2-Fluorobenzoate
            3-Fluorobenzoate
            4-Fluorobenzoate
PRODUCT     AMP
            Pyrophosphate
            Benzoyl-CoA
            2-Fluorobenzoyl-CoA
            3-Fluorobenzoyl-CoA
            4-Fluorobenzoyl-CoA
COMMENT     Also acts on 2-, 3- and 4- fluorobenzoate, but only very slowly
            on the corresponding chlorobenzoates.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 6.2.1.25
            WIT (What Is There) Metabolic Reconstruction: 6.2.1.25
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