ENTRY       EC 6.2.1.23
NAME        Dicarboxylate--CoA ligase
            Carboxylyl-CoA synthetase
CLASS       Ligases
            Forming carbon-sulfur bonds
            Acid--thiol ligases
SYSNAME     omega-Dicarboxylate:CoA ligase (AMP-forming)
REACTION    ATP + an alpha(omega)-Dicarboxylic acid = AMP + Pyrophosphate +
            an omega-Carboxyacyl-CoA
SUBSTRATE   ATP
            alpha(omega)-Dicarboxylic acid
            Dodecanedioic acid
PRODUCT     AMP
            Pyrophosphate
            omega-Carboxyacyl-CoA
COMMENT     Acts on dicarboxylic acids of chain length C5 to C16; the best
            substrate is dodecanedioic acid.
DBLINKS     University of Geneva ENZYME DATA BANK: 6.2.1.23
            WIT (What Is There) Metabolic Reconstruction: 6.2.1.23
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