ENTRY       EC 6.2.1.2
NAME        Butyrate--CoA ligase
            Butyryl-CoA synthetase
            Fatty acid thiokinase (medium chain)
            Acyl-activating enzyme
CLASS       Ligases
            Forming carbon-sulfur bonds
            Acid--thiol ligases
SYSNAME     Butanoate:CoA ligase (AMP-forming)
REACTION    ATP + an Acid + CoA = AMP + Pyrophosphate + an Acyl-CoA
SUBSTRATE   ATP
            Acid
            CoA
PRODUCT     AMP
            Pyrophosphate
            Acyl-CoA
COMMENT     Acts on acids from C4 to C11 and on the corresponding
            3-hydroxy- and 2,3- or 3,4-unsaturated acids.
PATHWAY     PATH: MAP00650  Butanoate metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 6.2.1.2
            WIT (What Is There) Metabolic Reconstruction: 6.2.1.2
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