ENTRY       EC 6.2.1.16
NAME        Acetoacetate--CoA ligase
            Acetoacetyl-CoA synthetase
CLASS       Ligases
            Forming carbon-sulfur bonds
            Acid--thiol ligases
SYSNAME     Acetoacetate:CoA ligase (AMP-forming)
REACTION    ATP + Acetoacetate + CoA = AMP + Pyrophosphate + Acetoacetyl-CoA
SUBSTRATE   ATP
            Acetoacetate
            CoA
PRODUCT     AMP
            Pyrophosphate
            Acetoacetyl-CoA
COMMENT     Also acts, more slowly, on L-3-hydroxybutanoate.
PATHWAY     PATH: MAP00650  Butanoate metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 6.2.1.16
            WIT (What Is There) Metabolic Reconstruction: 6.2.1.16
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