ENTRY       EC 6.1.1.7
NAME        Alanine--tRNA ligase
            Alanyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Alanine:tRNA(Ala) ligase (AMP-forming)
REACTION    ATP + L-Alanine + tRNA(Ala) = AMP + Pyrophosphate +
            L-Alanyl-tRNA(Ala)
SUBSTRATE   ATP
            L-Alanine
            tRNA(Ala)
PRODUCT     AMP
            Pyrophosphate
            L-Alanyl-tRNA(Ala)
PATHWAY     PATH: MAP00252  Alanine and Aspartate metabolism
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
DISEASE     MIM: 601065  Alanyl-tRNA synthetase
MOTIF       PS: PS00179  [FYH]-R-x-[DE]-x(4,12)-[RH]-x(3)-F-x(3)-[DE]
            PS: PS00339  [GSTALVF]-{DENQHRKP}-[GSTA]-[LIVMF]-[DE]-R-[LIVMF]-x-
                         [LIVMSTAG]-[LIVMFY]
GENES       MJA: MJ0564(alaS)
            MTH: MTH1683
            ECO: b2697(alaS)
            HIN: HI0814(alaS)
            HPY: HP1241(alaS)
            BSU: alaS
            MGE: MG292(alaS)
            MPN: A05_orf900(alaS)
            SYN: sll0362(alaS)
            SCE: YOR335C(ALA1)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.7
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.7
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