ENTRY       EC 6.1.1.17
NAME        Glutamate--tRNA ligase
            Glutamyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Glutamate:tRNA(Glu) ligase (AMP-forming)
REACTION    ATP + L-Glutamate + tRNA(Glu) = AMP + Pyrophosphate +
            L-Glutamyl-tRNA(Glu)
SUBSTRATE   ATP
            L-Glutamate
            tRNA(Glu)
PRODUCT     AMP
            Pyrophosphate
            L-Glutamyl-tRNA(Glu)
PATHWAY     PATH: MAP00251  Glutamate metabolism
            PATH: MAP00860  Porphyrin and chlorophyll metabolism
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
DISEASE     MIM: 138295  Glutamyl-prolyl-tRNA synthetase
MOTIF       PS: PS00178  P-x(0,2)-[GSTAN]-[DENGAPK]-x-[LIVMFP]-[HT]-[LIVMYAC]-G-
                         [HNTG]-[LIVMFYSTAGPC]
            PS: PS00179  [FYH]-R-x-[DE]-x(4,12)-[RH]-x(3)-F-x(3)-[DE]
            PS: PS00339  [GSTALVF]-{DENQHRKP}-[GSTA]-[LIVMF]-[DE]-R-[LIVMF]-x-
                         [LIVMSTAG]-[LIVMFY]
            PS: PS00762  Q-G-[DE]-x-[LIV]-[KR]-x(2)-K-x(2)-[KN]-[AS]-x(4)-[LIV]-
                         [DENK]-x(2)-V-x(2)-L-x(3)-K
GENES       MJA: MJ1377(gltX)
            MTH: MTH51(gltX)
            ECO: b2400(gltX)
            HIN: HI0274(gltX)
            HPY: HP0476(gltX)
            BSU: gltX
            MGE: MG462(gltX)
            MPN: K05_orf484(gltX)
            SYN: sll0179(gltX)
            SCE: YGL245W(G0583) YOL033W(MSE1)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.17
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.17
///