ENTRY       EC 6.1.1.16
NAME        Cysteine--tRNA ligase
            Cysteinyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Cysteine:tRNA(Cys) ligase (AMP-forming)
REACTION    ATP + L-Cysteine + tRNA(Cys) = AMP + Pyrophosphate +
            L-Cysteinyl-tRNA(Cys)
SUBSTRATE   ATP
            L-Cysteine
            tRNA(Cys)
PRODUCT     AMP
            Pyrophosphate
            L-Cysteinyl-tRNA(Cys)
PATHWAY     PATH: MAP00272  Cysteine metabolism
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
DISEASE     MIM: 123859  Cysteinyl-tRNA synthetase
MOTIF       PS: PS00178  P-x(0,2)-[GSTAN]-[DENGAPK]-x-[LIVMFP]-[HT]-[LIVMYAC]-G-
                         [HNTG]-[LIVMFYSTAGPC]
GENES       ECO: b0526(cysS)
            HIN: HI0078(cysS)
            HPY: HP0886(cysS)
            BSU: cysS(snpA)
            MGE: MG253(cysS)
            MPN: H91_orf437(cysS)
            SYN: slr0958(cysS)
            SCE: YNL247W(N0885)
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.16
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.16
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