ENTRY       EC 6.1.1.12
NAME        Aspartate--tRNA ligase
            Aspartyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Aspartate:tRNA(Asp) ligase (AMP-forming)
REACTION    ATP + L-Aspartate + tRNA(Asp) = AMP + Pyrophosphate +
            L-Aspartyl-tRNA(Asp)
SUBSTRATE   ATP
            L-Aspartate
            tRNA(Asp)
PRODUCT     AMP
            Pyrophosphate
            L-Aspartyl-tRNA(Asp)
PATHWAY     PATH: MAP00252  Alanine and Aspartate metabolism
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
MOTIF       PS: PS00179  [FYH]-R-x-[DE]-x(4,12)-[RH]-x(3)-F-x(3)-[DE]
            PS: PS00339  [GSTALVF]-{DENQHRKP}-[GSTA]-[LIVMF]-[DE]-R-[LIVMF]-x-
                         [LIVMSTAG]-[LIVMFY]
GENES       MJA: MJ1555(aspS)
            MTH: MTH226
            ECO: b1866(aspS)
            HIN: HI0317(aspS)
            HPY: HP0617(aspS)
            BSU: aspS
            MGE: MG036(aspS)
            MPN: D09_orf557(aspS)
            SYN: slr1720(aspS)
            SCE: YLL018C(DPS1) YPL104W(MSD1)
STRUCTURES  PDB: 1ASZ  1ASY  
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.12
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.12
            SCOP (Structural Classificaion of Proteins): 6.1.1.12
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