ENTRY       EC 6.1.1.10
NAME        Methionine--tRNA ligase
            Methionyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Methione:tRNA(Met) ligase (AMP-forming)
REACTION    ATP + L-Methionine + tRNA(Met) = AMP + Pyrophosphate +
            L-Methionyl-tRNA(Met)
SUBSTRATE   ATP
            L-Methionine
            tRNA(Met)
PRODUCT     AMP
            Pyrophosphate
            L-Methionyl-tRNA(Met)
PATHWAY     PATH: MAP00271  Methionine metabolism
            PATH: MAP00450  Selenoamino acid metabolism
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
MOTIF       PS: PS00178  P-x(0,2)-[GSTAN]-[DENGAPK]-x-[LIVMFP]-[HT]-[LIVMYAC]-G-
                         [HNTG]-[LIVMFYSTAGPC]
GENES       MJA: MJ1263(metS)
            MTH: MTH587
            ECO: b2114(metG)
            HIN: HI1276(metG)
            HPY: HP0417(metS)
            BSU: metS
            MGE: MG021(metS)
            MPN: B01_orf512(metS)
            SYN: slr0649(metS)
            SCE: YGR171C(MSM1) YGR264C(MES1)
            HSA: MARS
STRUCTURES  PDB: 0MTS  1MEA  1MED  
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.10
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.10
            SCOP (Structural Classificaion of Proteins): 6.1.1.10
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