ENTRY       EC 6.1.1.1
NAME        Tyrosine--tRNA ligase
            Tyrosyl-tRNA synthetase
CLASS       Ligases
            Forming carbon-oxygen bonds
            Ligases forming aminoacyl-tRNA and related compounds
SYSNAME     L-Tyrosine:tRNA(Tyr) ligase (AMP-forming)
REACTION    ATP + L-Tyrosine + tRNA(Tyr) = AMP + Pyrophosphate +
            L-Tyrosyl-tRNA(Tyr)
SUBSTRATE   ATP
            L-Tyrosine
            tRNA(Tyr)
PRODUCT     AMP
            Pyrophosphate
            L-Tyrosyl-tRNA(Tyr)
PATHWAY     PATH: MAP00400  Phenylalanine, tyrosine and tryptophan biosynthesis
            PATH: MAP01020  Protein biosynthesis (prokaryotes)
            PATH: MAP01030  Protein biosynthesis (eukaryotes)
MOTIF       PS: PS00178  P-x(0,2)-[GSTAN]-[DENGAPK]-x-[LIVMFP]-[HT]-[LIVMYAC]-G-
                         [HNTG]-[LIVMFYSTAGPC]
GENES       MJA: MJ0389(tyrS)
            MTH: MTH1767
            ECO: b1637(tyrS)
            HIN: HI1610(tyrS)
            HPY: HP0774(tyrS)
            BSU: tyrS tyrZ(ipa-9r)
            MGE: MG455(tyrS)
            MPN: K05_orf399(tyrS)
            SYN: slr1031(tyrS) ssr1720(tyrS)
            SCE: YGR185C(TYS1) YPL097W(MSY1)
STRUCTURES  PDB: 1TYA  1TYB  1TYC  1TYD  2TS1  3TS1  4TS1  
DBLINKS     University of Geneva ENZYME DATA BANK: 6.1.1.1
            WIT (What Is There) Metabolic Reconstruction: 6.1.1.1
            SCOP (Structural Classificaion of Proteins): 6.1.1.1
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