ENTRY EC 4.4.1.16
NAME Selenocysteine lyase
Selenocysteine reductase
CLASS Lyases
Carbon-sulfur lyases
SYSNAME L-Selenocysteine reductase
REACTION L-Selenocysteine + Reduced acceptor = Selenide + L-Alanine +
Acceptor
SUBSTRATE L-Selenocysteine
Reduced acceptor
Dithiothreitol
2-Mercaptoethanol
PRODUCT Selenide
L-Alanine
Acceptor
COFACTOR Pyridoxal phosphate
COMMENT A pyridoxal-phosphate protein. Dithiothreitol or 2-mercaptoethanol
can act as reducing agent in the reaction. The enzyme does not act
on cysteine, serine or chloroalanine.
PATHWAY PATH: MAP00450 Selenoamino acid metabolism
DBLINKS University of Geneva ENZYME DATA BANK: 4.4.1.16
WIT (What Is There) Metabolic Reconstruction: 4.4.1.16
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