ENTRY       EC 4.2.1.61
NAME        3-Hydroxypalmitoyl-[acyl-carrier-protein] dehydratase
CLASS       Lyases
            Carbon-oxygen lyases
            Hydro-lyases
SYSNAME     (3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase
REACTION    (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] =
            2-Hexadecenoyl-[acyl-carrier protein] + H2O
SUBSTRATE   (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
PRODUCT     2-Hexadecenoyl-[acyl-carrier protein]
            H2O
COMMENT     Is specific for 3-hydroxyacyl-[acyl-carrier protein] derivatives
            (C12 to C16) and has the highest activity on the C16 derivative.
PATHWAY     PATH: MAP00061  Fatty acid biosynthesis (path 1)
DISEASE     MIM: 600212  Fatty acid synthase
MOTIF       PS: PS00012  [DEQGSTALMKRH]-[LIVMFYSTAC]-[GNQ]-[LIVMFYAG]-[DNEKHS]-
                         S-[LIVMST]-{PCFY}-[STAGCPQLIMF]-[LIVMATN]-
                         [DENQGTAKRHLM]-[LIVMWSTA]-[LIVGSTACR]-x(2)-[LIVMFA]
            PS: PS00606  G-x(4)-[LIVMFAP]-x(2)-[AGC]-C-[STA](2)-[STAG]-x(3)-
                         [LIVMF]
GENES       SCE: YKL182W(FAS1)
DBLINKS     University of Geneva ENZYME DATA BANK: 4.2.1.61
            WIT (What Is There) Metabolic Reconstruction: 4.2.1.61
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