ENTRY       EC 4.2.1.52
NAME        Dihydrodipicolinate synthase
CLASS       Lyases
            Carbon-oxygen lyases
            Hydro-lyases
SYSNAME     L-Aspartate-4-semialdehyde hydro-lyase
            (adding pyruvate and cyclizing)
REACTION    L-Aspartate 4-semialdehyde + Pyruvate = 2,3-Dihydrodipicolinate +
            2 H2O
SUBSTRATE   L-Aspartate 4-semialdehyde
            Pyruvate
PRODUCT     2,3-Dihydrodipicolinate
            H2O
PATHWAY     PATH: MAP00300  Lysine biosynthesis
MOTIF       PS: PS00665  [GSA]-[LIVM]-[LIVMFY]-x(2)-G-[ST]-[TG]-G-E-[GASNF]-
                         x(6)-[EQ]
            PS: PS00666  Y-[DNS]-[LIVMF]-P-x(2)-[ST]-x(3)-[LIVM]-x(13,14)-
                         [LIVM]-x-[AG]-[LIVM]-K-[DEQF]-[STAC]
GENES       MJA: MJ0244(dapA)
            MTH: MTH801
            ECO: b2478(dapA)
            HIN: HI0255(dapA)
            HPY: HP1013(dapA)
            BSU: dapA
            SYN: slr0550(dapA)
STRUCTURES  PDB: 1DHP  
DBLINKS     University of Geneva ENZYME DATA BANK: 4.2.1.52
            WIT (What Is There) Metabolic Reconstruction: 4.2.1.52
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