ENTRY       EC 4.2.1.51
NAME        Prephenate dehydratase
CLASS       Lyases
            Carbon-oxygen lyases
            Hydro-lyases
SYSNAME     Prephenate hydro-lyase (decarboxylating)
REACTION    Prephenate = Phenylpyruvate + H2O + CO2
SUBSTRATE   Prephenate
            Chorismate
PRODUCT     Phenylpyruvate
            H2O
            CO2
            Prephenate
COMMENT     This enzyme in the enteric bacteria also possesses chorismate
            mutase activity and converts chorismate into prephenate.
PATHWAY     PATH: MAP00400  Phenylalanine, tyrosine and tryptophan biosynthesis
MOTIF       PS: PS00857  [FY]-x-[LIVM]-x(2)-[LIVM]-x(5)-[DN]-x(5)-T-R-F-[LIVMW]-
                         x-[LIVM]
            PS: PS00858  [LIVM]-[ST]-[KR]-[LIVM]-E-[ST]-R-P
            PS: PS01039  G-[FYI]-[DE]-[VILMT]-[DE]-[VILM]-x(3)-[LIVMA]-[AC]-
                         x(2)-[LIVMAG]
GENES       MJA: MJ0637(pheA)
            ECO: b2599(pheA)
            HIN: HI1145(pheA)
            BSU: pheA
            SCE: YNL316C(PHA2)
DBLINKS     University of Geneva ENZYME DATA BANK: 4.2.1.51
            WIT (What Is There) Metabolic Reconstruction: 4.2.1.51
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