ENTRY       EC 4.2.1.19
NAME        Imidazoleglycerol-phosphate dehydratase
CLASS       Lyases
            Carbon-oxygen lyases
            Hydro-lyases
SYSNAME     D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate hydro-lyase
REACTION    D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate =
            3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O
SUBSTRATE   D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
PRODUCT     3-(Imidazol-4-yl)-2-oxopropyl phosphate
            H2O
PATHWAY     PATH: MAP00340  Histidine metabolism
MOTIF       PS: PS00954  [LIVM]-D-x-H-H-x(2)-E-x(2)-[GCA]-[LIVM]-[AT]-[LIVM]
            PS: PS00955  G-x-N-x-H-H-x(2)-E-[STAGC]-x-[FY]-K
GENES       MJA: MJ0698(hisB)
            MTH: MTH1467(hisB)
            ECO: b2022(hisB)
            HIN: HI0471(hisB)
            BSU: hisB
            SYN: sll0084(hisB_1) slr0500(hisB)
            SCE: YOR202W(HIS3)
DBLINKS     University of Geneva ENZYME DATA BANK: 4.2.1.19
            WIT (What Is There) Metabolic Reconstruction: 4.2.1.19
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