ENTRY       EC 4.2.1.16
NAME        Threonine dehydratase
            Threonine deaminase
            L-Serine dehydratase
            Serine deaminase
CLASS       Lyases
            Carbon-oxygen lyases
            Hydro-lyases
SYSNAME     L-Threonine hydro-lyase (deaminating)
REACTION    L-Threonine + H2O = 2-Oxobutanoate + NH3 + H2O
SUBSTRATE   L-Threonine
            L-Serine
            H2O
PRODUCT     2-Oxobutanoate
            2-Oxopropanoate
            NH3
            H2O
COFACTOR    Pyridoxal phosphate
COMMENT     The enzyme from many sources is a pyridoxal-phosphate protein;
            that from P.putida is not. The enzyme from a number of sources
            also acts on L-serine. (cf. EC 4.2.1.13 L-Serine dehydratase)
PATHWAY     PATH: MAP00260  Glycine, serine and threonine metabolism
MOTIF       PS: PS00165  [DESH]-x(4,5)-[STVG]-x-[AS]-[FYI]-K-[DLIFSA]-[RVMF]-
                         [GA]-[LIVMGA]
GENES       ECO: b3117(tdcB) b3772(ilvA)
            HIN: HI0738B(ilvA)
            BSU: ilvA
            SYN: slr2072(ilvA)
            SCE: YCL064C(CHA1) YER086W(ILV1)
DBLINKS     University of Geneva ENZYME DATA BANK: 4.2.1.16
            WIT (What Is There) Metabolic Reconstruction: 4.2.1.16
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