ENTRY       EC 4.1.99.2
NAME        Tyrosine phenol-lyase
            beta-Tyrosinase
CLASS       Lyases
            Carbon-carbon lyases
            Other carbon-carbon lyases
SYSNAME     L-Tyrosine phenol-lyase (deaminating)
REACTION    L-Tyrosine + H2O = Phenol + Pyruvate + NH3
SUBSTRATE   L-Tyrosine
            H2O
PRODUCT     Phenol
            Pyruvate
            NH3
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal phosphate protein. The enzyme also slowly catalyses
            pyruvate formation from D-tyrosine, S-methyl-L-cysteine,
            L-cysteine, L-serine and D-serine.
PATHWAY     PATH: MAP00350  Tyrosine metabolism
            PATH: MAP00910  Nitrogen metabolism
MOTIF       PS: PS00853  Y-x-D-x(3)-M-S-[GA]-K-K-D-x-[LIVM](2)-x-[LIVM]-G-G
STRUCTURES  PDB: 1TPL  2TPL  
DBLINKS     University of Geneva ENZYME DATA BANK: 4.1.99.2
            WIT (What Is There) Metabolic Reconstruction: 4.1.99.2
            SCOP (Structural Classificaion of Proteins): 4.1.99.2
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