ENTRY       EC 4.1.3.31
NAME        2-Methylcitrate synthase
CLASS       Lyases
            Carbon-carbon lyases
            Oxo-acid-lyases
SYSNAME     2-Methylcitrate oxaloacetate-lyase
REACTION    2-Methylcitrate + CoA = Propanoyl-CoA + H2O + Oxaloacetate
SUBSTRATE   2-Methylcitrate
            CoA
PRODUCT     Propanoyl-CoA
            H2O
            Oxaloacetate
COMMENT     The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and
            petanoyl-CoA. The relative rate of condensation of acetyl-CoA and
            oxaloacetate is 1401436424f that of propanoyl-CoA and oxaloacetate but
            the enzyme has been separated from EC 4.1.3.7.  Oxaloacetate
            cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate.
PATHWAY     PATH: MAP00640  Propanoate metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 4.1.3.31
            WIT (What Is There) Metabolic Reconstruction: 4.1.3.31
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