ENTRY       EC 4.1.1.17
NAME        Ornithine decarboxylase
CLASS       Lyases
            Carbon-carbon lyases
            Carboxy-lyases
SYSNAME     L-Ornithine carboxy-lyase
REACTION    L-Ornithine = Putrescine + CO2
SUBSTRATE   L-Ornithine
PRODUCT     Putrescine
            CO2
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein.
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00330  Arginine and proline metabolism
DISEASE     MIM: 165640  Ornithine decarboxylase-1
MOTIF       PS: PS00703  [STAV]-x-S-x-H-K-x(2)-[GSTAN](2)-x-[STA]-Q-[STA](2)
            PS: PS00878  [FY]-[PA]-x-K-[SACV]-x(5)-[LIVM]-[LIVMA]-x(2)-[LIVMA]-
                         x(3)-G
            PS: PS00879  [LIVMSC]-x(2)-[LIVMF]-[DNS]-[LIVMCA]-G-G-G-[LIVMFY]-
                         x(0,1)-[GSF]
GENES       ECO: b0693(speF) b2965(speC)
            HIN: HI0591(speF)
            SCE: YKL184W(ORD1)
            HSA: ODC1(Hs.75212)
STRUCTURES  PDB: 1ORD  
DBLINKS     University of Geneva ENZYME DATA BANK: 4.1.1.17
            WIT (What Is There) Metabolic Reconstruction: 4.1.1.17
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