ENTRY       EC 3.7.1.3
NAME        Kynureninase
CLASS       Hydrolases
            Acting on carbon-carbon bonds
            In ketonic substances
SYSNAME     L-Kynurenine hydrolase
REACTION    L-Kynurenine + H2O = Anthranilate + L-Alanine
SUBSTRATE   L-Kynurenine
            H2O
            3-Hydroxykynurenine
            (3-Arylcarbonyl)-alanine
PRODUCT     Anthranilate
            L-Alanine
            3-Hydroxyanthranilate
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. Also acts on 3'-hydroxykynurenine
            and some other (3-arylcarbonyl)-alanines.
PATHWAY     PATH: MAP00380  Tryptophan metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 3.7.1.3
            WIT (What Is There) Metabolic Reconstruction: 3.7.1.3
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