ENTRY       EC 3.6.1.5
NAME        Apyrase
            ATP-diphosphatase
            Adenosine diphosphatase
            ADPase
CLASS       Hydrolases
            Acting on acid anhydrides
            In phosphorus-containing anhydrides
SYSNAME     ATP diphosphohydrolase
REACTION    ATP + 2 H2O = AMP + 2 Orthophosphate
SUBSTRATE   ATP
            H2O
            ADP
PRODUCT     AMP
            Orthophosphate
COFACTOR    Calcium
COMMENT     Requires Ca2+. Also acts on ADP, and on other nucleoside
            triphosphates and diphosphates.
PATHWAY     PATH: MAP00230  Purine metabolism
            PATH: MAP00240  Pyrimidine metabolism
DISEASE     MIM: 601752  CD39 antigen
DBLINKS     University of Geneva ENZYME DATA BANK: 3.6.1.5
            WIT (What Is There) Metabolic Reconstruction: 3.6.1.5
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