ENTRY       EC 3.6.1.45
NAME        UDP-sugar siphosphatase
            UDP-sugar pyrophosphatase
            Nucleosidesiphosphate-sugar pyrophosphatase
            UDP-sugar hydrolase
CLASS       Hydrolases
            Acting on acid anhydrides
            In phosphorus-containing anhydrides
REACTION    UDP-sugar + H2O = UMP + Sugar 1-phosphate
SUBSTRATE   UDP-sugar
            H2O
PRODUCT     UMP
            Sugar 1-phosphate
COMMENT     UDP-sugar is the best substrate,although other nucleoside-
            sugar diphosphates are used as substrates with similar KM
            values but much lower maximum velocities. Thus this enzyme
            has a distinct specificity from ADP-sugar pyrophosphatase
            (EC 3.6.1.21).
            Some but not all enzymes of this class also appear to have
            5'-Nucleotidase (EC 3.1.3.5) activity.
PATHWAY     PATH: MAP00530  Aminosugars metabolism
MOTIF       PS: PS00785  [LIVM]-x-[LIVM](2)-[HEA]-[TI]-x-D-x-H-[GSA]
            PS: PS00786  [FY]-x(4)-[LIVM]-G-N-H-E-F-[DN]
GENES       ECO: b0480(ushA)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.6.1.45
            WIT (What Is There) Metabolic Reconstruction: 3.6.1.45
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