ENTRY EC 3.6.1.41
NAME Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
Diadenosinetetraphosphatase (symmetrical)
Dinucleosidetetraphosphate (symmetrical)
CLASS Hydrolases
Acting on acid anhydrides
In phosphorus-containing anhydrides
SYSNAME P1,P4-Dis(5'-nucleosyl)-tetraphosphate
nucleotidebisphosphohydrolase
REACTION P1,P4-Bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP
SUBSTRATE P1,P4-Bis(5'-adenosyl) tetraphosphate
H2O
Bis(5'-guanosyl) tetraphosphate
Bis(5'-adenosyl) pentaphosphate
PRODUCT ADP
GDP
COMMENT Also acts on bis(5'-guanosyl) tetraphosphate and bis(5'-adenosyl)
pentaphosphate, and, more slowly, on some other polyphosphates,
forming a nucleoside bisphosphate as one product in all cases (cf.
EC 3.6.1.17).
PATHWAY PATH: MAP00230 Purine metabolism
GENES ECO: b0049(apaH)
HIN: HI0551(apaH)
BSU: yjbP
DBLINKS University of Geneva ENZYME DATA BANK: 3.6.1.41
WIT (What Is There) Metabolic Reconstruction: 3.6.1.41
///
DBGET integrated database retrieval system,
GenomeNet