ENTRY EC 3.6.1.35
NAME H+-transporting ATPase
CLASS Hydrolases
Acting on acid anhydrides
In phosphorus-containing anhydrides
SYSNAME ATP phosphohydrolase(H+-transporting, acyl-phosphate-linked)
REACTION ATP + H2O = ADP + Orthophosphate
SUBSTRATE ATP
H2O
PRODUCT ADP
Orthophosphate
COFACTOR H+
COMMENT A gorup of enzymes from the plasma membranes of yeast and
Neurospora. They are closely related to the H+/K+-transporting
ATPases (EC 3.6.1.36), have a single catalytic sub-unit (100 kDa)
and form phosphoenyzme intermediates. Formerly included with
EC 3.6.1.3.
DISEASE MIM: 192132 Vacuolar proton pump-3 (58kD subunit)
MOTIF PS: PS00154 D-K-T-G-T-[LIVM]-[TI]
GENES MJA: MJ1226
MTH: MTH1001 MTH481 MTH482
SCE: YGL008C(PMA1) YPL036W(PMA2)
DBLINKS University of Geneva ENZYME DATA BANK: 3.6.1.35
WIT (What Is There) Metabolic Reconstruction: 3.6.1.35
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