ENTRY       EC 3.6.1.17
NAME        Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
            Bis(5'-guanosyl)-tetraphosphatase
            Bis(5'-adenosyl)-tetraphosphatase
            Diguanosinetetraphosphatase (asymmetrical)
            Dinucleosidetetraphosphatase (asymmetrical)
            Diadenosine P1,P4-tetraphosphatase
CLASS       Hydrolases
            Acting on acid anhydrides
            In phosphorus-containing anhydrides
SYSNAME     P1,P4-Bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase
REACTION    P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP
SUBSTRATE   P1,P4-Bis(5'-guanosyl) tetraphosphate
            H2O
            P1,P4-Bis(5'-xantosyl) tetraphosphate
PRODUCT     GTP
            GMP
            XTP
            XMP
COMMENT     Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly,
            on bis(5'-adenosyl)-tetraphosphate and
            bis(5'-uridyl)-tetraphosphate (cf. EC 3.6.1.41).
DBLINKS     University of Geneva ENZYME DATA BANK: 3.6.1.17
            WIT (What Is There) Metabolic Reconstruction: 3.6.1.17
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