ENTRY       EC 3.5.4.6
NAME        AMP deaminase
            Adenylic acid deaminase
            AMP aminase
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In cyclic amidines
SYSNAME     AMP aminohydrolase
REACTION    AMP + H2O = IMP + NH3
SUBSTRATE   AMP
            H2O
PRODUCT     IMP
            NH3
COMMENT     (cf. EC 3.5.4.17)
PATHWAY     PATH: MAP00230  Purine metabolism
DISEASE     MIM: 102770  Adenosine monophosphate deaminase-1 (muscle);
                         Myoadenylate deaminase deficiency (3)
            MIM: 102771  Adenosine monophosphate deaminase-2 (isoform L)
            MIM: 102772  Adenosine monophosphate deaminase 3 (isoform E); [AMP
                         deaminase deficiency, erythrocytic] (3)
MOTIF       PS: PS00485  S-[LIVM]-[NS]-T-D-D-P
GENES       SCE: YML035C(AMD1)
            HSA: AMPD1 AMPD2 AMPD3(Hs.83918)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.4.6
            WIT (What Is There) Metabolic Reconstruction: 3.5.4.6
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