ENTRY       EC 3.5.4.20
NAME        Pyrithiamin deaminase
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In cyclic amidines
SYSNAME     1-(4-Amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-
            $2-methylpyridinium-bromide aminohydrolase
REACTION    1-(4-Amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-
            $2-methylpyridinium bromide + H2O =
            1-(4-Hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-
            $2-methylpyridinium bromide + NH3
SUBSTRATE   1-(4-Amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-
            $2-methylpyridinium bromide
            H2O
PRODUCT     1-(4-Hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-
            $2-methylpyridinium bromide
            NH3
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.4.20
            WIT (What Is There) Metabolic Reconstruction: 3.5.4.20
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