ENTRY       EC 3.5.2.3
NAME        Dihydroorotase
            Carbamoylaspartic dehydrase
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In cyclic amides
SYSNAME     (S)-Dihydroorotate amidohydrolase
REACTION    (S)-Dihydroorotate + H2O = N-Carbamoyl-L-aspartate
SUBSTRATE   (S)-Dihydroorotate
            H2O
PRODUCT     N-Carbamoyl-L-aspartate
PATHWAY     PATH: MAP00240  Pyrimidine metabolism
MOTIF       PS: PS00097  F-x-[EK]-x-S-[GT]-R-T
            PS: PS00442  [PAS]-[LIVMFYT]-[LIVMFY]-G-[LIVMFY]-C-[LIVMFYN]-G-x-
                         [QE]-x-[LIVMFA]
            PS: PS00482  D-[LIVMFYWSP]-H-[LIV]-H-[LIVF]-[RN]-x-[PG]
            PS: PS00483  [GA]-[ST]-D-x-A-P-H-x(4)-K
            PS: PS00866  [FYV]-P-[LIVMC]-[LIVMA]-[LIVM]-[KR]-[PSA]-[STA]-x(3)-
                         [SG]-G-x-[AG]
            PS: PS00867  [LIVMF]-[LIMN]-E-[LIVMCA]-N-[PATLIVM]-[KR]-[LIVMSTAC]
GENES       MJA: MJ1490
            MTH: MTH1127
            ECO: b1062(pyrC)
            HPY: HP0266(pyrC) HP0581(pyrC)
            BSU: pyrC
            SYN: sll1018(pyrC) slr0406(pyrC)
            SCE: YLR420W(URA4)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.2.3
            WIT (What Is There) Metabolic Reconstruction: 3.5.2.3
///