ENTRY EC 3.5.1.76
NAME Arylalkyl acylamidase
CLASS Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
REACTION N-Acetylarylalkylamine + H2O = Arylalkylamine + Acetate
SUBSTRATE N-Acetylarylalkylamine
H2O
PRODUCT Arylalkylamine
Acetate
COMMENT Strict specificity for N-Acetyl arylalkylamines, including
N-Acetyl-2-phenylethylamide, N-Acetyl-3-phenylpropylamine,
N-Acetyldopamine, N-Acetylserotonin and Melatonin. It also
accepts Arylalkyl acetates but not Acetanilide derivatives,
which are common substrates of Aryl acylamidase
(EC 3.5.1.13).
DBLINKS University of Geneva ENZYME DATA BANK: 3.5.1.76
WIT (What Is There) Metabolic Reconstruction: 3.5.1.76
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