ENTRY EC 3.5.1.69
NAME Glycosphingolipid deacylase
Glycosphingolipid ceramide deacylase
CLASS Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
SYSNAME Glycosphingolipid amidohydrolase
REACTION Hydrolysis of gangliosides and neutral glycosphingolipids,
releasing fatty acids to form the lyso-derivatives
SUBSTRATE Ganglioside
Neutral glycosphingolipid
H2O
PRODUCT Fatty acid
COMMENT Does not act on sphingolipids such as ceramide. Not identical with
EC 3.5.1.23.
DBLINKS University of Geneva ENZYME DATA BANK: 3.5.1.69
WIT (What Is There) Metabolic Reconstruction: 3.5.1.69
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