ENTRY EC 3.5.1.54
NAME Allophanate hydrolase
CLASS Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
SYSNAME Urea-1-carboxylate amidohydrolase
REACTION Urea-1-carboxylate + H2O = 2 CO2 + 2 NH3
SUBSTRATE Urea-1-carboxylate
H2O
PRODUCT CO2
NH3
COMMENT The yeast enzyme (but not that from green algae) also catalyses
the reaction of EC 6.3.4.6, thus bringing about the hydrolysis of
urea to CO2 and NH3 in the presence of ATP and bicarbonate.
PATHWAY PATH: MAP00220 Urea cycle and metabolism of amino groups
MOTIF PS: PS00188 [GN]-[DEQ]-x-[LIVMFY]-x(2)-[LIVM]-x-[AIV]-M-K-[LMA]-
x(3)-[LIVM]-x-[SA]
PS: PS00866 [FYV]-P-[LIVMC]-[LIVMA]-[LIVM]-[KR]-[PSA]-[STA]-x(3)-
[SG]-G-x-[AG]
PS: PS00867 [LIVMF]-[LIMN]-E-[LIVMCA]-N-[PATLIVM]-[KR]-[LIVMSTAC]
DBLINKS University of Geneva ENZYME DATA BANK: 3.5.1.54
WIT (What Is There) Metabolic Reconstruction: 3.5.1.54
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