ENTRY       EC 3.5.1.38
NAME        Glutamin-(asparagin-)ase
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In linear amides
SYSNAME     L-Glutamate(L-asparagine) amidohydrolase
REACTION    L-Glutamine + H2O = L-Glutamate + NH3
SUBSTRATE   L-Glutamine
            L-Asparagine
            H2O
PRODUCT     L-Glutamate
            L-Aspartate
            NH3
COMMENT     A-Asparagine is hydrolysed at 0.8 of the rate of L-glutamine; the
            the D-isomers are also hydrolysed, more slowly.
PATHWAY     PATH: MAP00251  Glutamate metabolism
            PATH: MAP00252  Alanine and Aspartate metabolism
            PATH: MAP00471  D-Glutamine and D-glutamate metabolism
            PATH: MAP00910  Nitrogen metabolism
MOTIF       PS: PS00144  [LIVM]-x(2)-T-G-G-T-I-[AG]
            PS: PS00917  G-x-[LIVM]-x(2)-H-G-T-D-T-[LIVM]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.1.38
            WIT (What Is There) Metabolic Reconstruction: 3.5.1.38
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