ENTRY EC 3.5.1.36
NAME N-Methyl-2-oxoglutaramate hydrolase
5-Hydroxy-N-methylpyroglutamate synthase
CLASS Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
SYSNAME N-Methyl-2-oxoglutaramate methylamidohydrolase
REACTION N-Methyl-2-oxoglutaramate + H2O = 2-Oxoglutarate + Methylamine
SUBSTRATE N-Methyl-2-oxoglutaramate
H2O
PRODUCT 2-Oxoglutarate
Methylamine
COMMENT In the reverse reaction, the product cyclizes non-enzymically to
2-hydroxy-N-methyl-5-oxoproline.
DBLINKS University of Geneva ENZYME DATA BANK: 3.5.1.36
WIT (What Is There) Metabolic Reconstruction: 3.5.1.36
///
DBGET integrated database retrieval system,
GenomeNet