ENTRY       EC 3.5.1.14
NAME        Aminoacylase
            Dehydropeptidase II
            Histozyme
            Hippuricase
            Benzamidase
            Acylase I
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In linear amides
SYSNAME     N-Acyl-L-amino-acid amidohydrolase
REACTION    an N-Acyl-L-amino acid + H2O = a Carboxylate + an L-Amino acid
SUBSTRATE   N-Acyl-L-amino acid
            H2O
            Dehydropeptide
PRODUCT     Carboxylate
            L-Amino acid
COMMENT     Wide specificity; also hydrolyses dehydropeptides. Used in
            separating D- and L- amino acids.
DISEASE     MIM: 104620  Aminoacylase-1
MOTIF       PS: PS00758  [LI]-[GAL]-[LIVMF]-x-[GSA]-H-x-D-[TV]-[STAV]
            PS: PS00759  [GSTAI]-[SANQ]-D-x-K-[GSACN]-x(2)-[LIVMA]-x(2)-
                         [LIVMFY]-x(14,17)-[LIVM]-x-[LIVMF]-[LIVMSTAG]-[LIVMFA]-
                         x(2)-[DN]-E-E-x-[GSTN]
GENES       SYN: sll0100
            HSA: ACY1(Hs.79)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.1.14
            WIT (What Is There) Metabolic Reconstruction: 3.5.1.14
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