ENTRY EC 3.4.99.41
NAME Mitochondrial processing peptidase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Endopeptidases of unknown catalytic mechanism
REACTION Cleavage of the leader peptides from precursor proteins imported
into the mitochondrion, typically with Arg in position P2.
SUBSTRATE Protein
H2O
PRODUCT Protein
Peptide
COMMENT Known from the mitochondrial matrix of fungi and mammals. A
homologue of insulinase.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.99.41
WIT (What Is There) Metabolic Reconstruction: 3.4.99.41
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