ENTRY EC 3.4.24.6
NAME Leucolysin
Leucostoma neutral proteinase
Leucostoma peptidase A
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Metalloendopeptidases
REACTION Cleavage of Phe1+Val, His5+Leu, Ala14+Leu, Gly20+Glu, Gly23+Phe
and Phe24+Phe bonds in insulin B chain as well as N-blocked
dipeptides.
SUBSTRATE Protein
Peptide
H2O
PRODUCT Protein
Peptide
COFACTOR Metal
COMMENT From the venom of the western cottonmouth moccasin snake
(Agkistrodon piscivorus leucostoma).
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.24.6
WIT (What Is There) Metabolic Reconstruction: 3.4.24.6
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