ENTRY       EC 3.4.24.53
NAME        Trimerelysin II
            Trimeresurus metalloendopeptidase II
            Proteinase H2
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Cleavage of Asn3+Gln, His10+Leu and Ala14+Leu in the insulin B
            chain, and the bond Z-Gly-Pro+Leu-Gly-Pro in a small molecule
            substrate of microbial collagenase
SUBSTRATE   Protein
            Peptide
            H2O
            Z-Gly-Pro-Leu-Gly-Pro
PRODUCT     Protein
            Peptide
            Z-Gly-Pro
            Leu-Gly-Pro
COMMENT     A 24 kDa nonhemorrhagic endopeptidase from the venom of the habu
            snake (Trimeresurus flavoviridis).
MOTIF       PS: PS00142  [GSTALIVN]-x(2)-H-E-[LIVMFYW]-{DEHRKP}-H-x-
                         [LIVMFYWGSPQ]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.53
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.53
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