ENTRY       EC 3.4.24.48
NAME        Ruberlysin
            Crotalus ruber metalloendopeptidase II
            Hemorrhagic toxin II
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Cleavage of His10+Leu, Ala14+Leu, Tyr16+Leu and Gly23+Phe bonds of
            the B chain of insulin; His+Pro, Pro+Phe, and Trp+Ser of
            angiotensin I; and Gly+Phe of Met enkephalin
SUBSTRATE   Protein
            Peptide
            H2O
            Fibrinogen
PRODUCT     Protein
            Peptide
COMMENT     A 25 kDa hemorrhagic endopeptidase from the venom of the red
            rattlesnake (Crotalus ruber ruber) that cleaves fibrinogen.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.48
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.48
///