ENTRY       EC 3.4.24.41
NAME        Atrolysin B
            Crotalus atrox metalloendopeptidase b
            Hemorrhagic toxin b (Ht-b)
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Cleavage of His5+Leu, His10+Leu, Ala14+Leu, Tyr16+Leu and
            Gly23+Phe of insulin B chain; identical to the cleavage of
            insulin B chain by atrolysin C. Also cleaves +Ser bonds in
            glucagon.
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COFACTOR    Metal
COMMENT     From the venom of the western diamondback rattlesnake (Crotalus
            atrox).  Mr = 24 kDa.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.41
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.41
///