ENTRY       EC 3.4.24.28
NAME        Bacillolysin
            Bacillus metalloendopeptidase
            Bacillus subtilis neutral proteinase
            Megateriopeptidase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Similar, but not identical, to that of thermolysin
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     Variants of this enzyme have been found in species of Bacillus
            including B. subtilis, B. amyloliquefaciens, B. megaterium
            (megateriopeptidase), B. mesentericus, B. cereus and
            B. stearothermophilus.  Formerly included in EC 3.4.24.4.
MOTIF       PS: PS00142  [GSTALIVN]-x(2)-H-E-[LIVMFYW]-{DEHRKP}-H-x-
                         [LIVMFYWGSPQ]
GENES       BSU: nprE
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.28
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.28
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