ENTRY EC 3.4.24.25
NAME Aeromonolysin
Aeromonas proteolytica neutral proteinase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Metalloendopeptidases
REACTION Preferential cleavage of bonds with bulky hydrophobic groups in
P2 and P1'.
SUBSTRATE Protein
Peptide
H2O
PRODUCT Protein
Peptide
COFACTOR Metal
COMMENT Thermostable enzyme from Aeromonas proteolytica. Specificity
related to, but distinct from, those of thermolysin and Bacillus
subtilis endopeptidase. Formerly included in EC 3.4.24.4.
MOTIF PS: PS00142 [GSTALIVN]-x(2)-H-E-[LIVMFYW]-{DEHRKP}-H-x-
[LIVMFYWGSPQ]
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.24.25
WIT (What Is There) Metabolic Reconstruction: 3.4.24.25
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