ENTRY       EC 3.4.24.21
NAME        Astacin
            Astacus proteinase
            Crayfish small-molecule proteinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Hydrolysis of peptide bonds in substrates containing five or more
            amino acids, preferentially with Ala in P1', and Pro in P2'
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     A 22.6 kDa digestive endopeptidase from the cardia of the crayfish
            Astacus fluviatilis.  Formerly EC 3.4.99.6.
MOTIF       PS: PS00142  [GSTALIVN]-x(2)-H-E-[LIVMFYW]-{DEHRKP}-H-x-
                         [LIVMFYWGSPQ]
STRUCTURES  PDB: 1IAE  1IAD  1AST  1IAA  1IAB  1IAC  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.21
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.21
            SCOP (Structural Classificaion of Proteins): 3.4.24.21
///